The Istituto di Ricerche Farmacologiche Mario Negri IRCCS, with three locations in Milan and Bergamo, is a private non-profit foundation since 1961.

The institute conducts research in biomedical field at the service of public health.  In 2018 Silvio Garattini became president, leaving the direction of the Institute to Giuseppe Remuzzi, former director of the Bergamo offices.

Independent from commercial interests, political parties, religious beliefs. It chooses not to patent its research to make it available to the scientific community and patients.

The research activity involves 700 researchers in 10 departments and focuses mainly on cancer, rare diseases, cardiovascular diseases, neurodegenerative diseases, kidney diseases, transplantation.

The over 15,000 scientific publications attest to the international recognition of the Institute, always at the side of the patient.